Enge lab publications
Selected publications, reverse chronological order
1. The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms
Yuanyuan Zhang, Yumeng Zhang, Evelyn Hutterer, Sara Hultin, Otto Bergman, Solrun Kolbeinsdottir, Hong Jin, Maria J Forteza, Daniel FJ Ketelhuth, Joy Roy, Ulf Hedin, Martin Enge,
Ljubica Matic, Per Eriksson, Lars Holmgren.
Nature Cardiovascular Research. 629-644 (2023)
2. Shared requirement for MYC upstream super-enhancer in tissue regeneration and cancer
Inderpreet Kaur Sur, Wenshuo Zhao, Jilin Zhang, Margareta Kling Pilström, Björn Rozell, Anna T Webb, Huaitao Cheng, Ari Ristimäki, Pekka Katajisto, Martin Enge,
Helena Rannikmae, Marc de la Roche, Jussi Taipale.
bioRxiv 2022/11/5.
3. An unsupervised and broadly applicable method for physical cell interaction profiling of complex tissues.
Nathanael Andrews, Jason Tyler Serviss, Natalie Geyer, Agneta Andersson, Ewa Dzwonkowska, Rosan Heijboer, Ninib Baryawno, Marco Gerling, Martin Enge.
Nature Methods volume 18, 912–920 (2021)
4. Spinal Cord Injury Induces Permanent Re-Programming of Microglia into a Disease-Associated State which Contributes to Functional Recovery
Hakim R, Zachariadis V, Sankavaram SR, Han J, Harris RA, Brundin L, *Enge M and *Svensson M; * corresponding authors
Journal of Neuroscience 20 August 2021, JN-RM-0860-21;
5. A highly scalable method for joint whole genome sequencing and gene expression profiling of single cells. Vasilios Zachariadis, Huaitao Cheng, Nathanael J Andrews, Martin Enge.
Molecular Cell, 80:3, 5 Nov. 2020. pp541-553.e5
6. Single cell analysis of human pancreas reveals transcriptional signatures of aging and somatic mutation patterns.
Enge M, Arda HE, Mignardi M, Kim SK & Quake, SR.
Cell. 2017 Oct 5;171(2):321-330.e14. doi: 10.1016/j.cell.2017.09.004.
7. DNA-dependent formation of transcription factor pairs alters their binding specificity
Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J
Nature 527, 384–388 (19 November 2015).
8. CTCF/cohesin binding sites are frequently mutated in cancer.
Katainen R, Dave K , Pitkänen E, Palin K, Kivioja T, Välimäki N, Gylfe A, Ristolainen H, Hänninen U, Cajuso T, Kondelin J, Tanskanen T, Mecklin JP, Järvinen H, Renkonen--Sinisalo L, Lepistö A, Kaasinen E, Kilpivaara O, Tuupanen S, Enge M, Taipale J, Aaltonen L
Nature Genetics, 47, 818–821 (2015)
9. Transcription Factor Binding in Human Cells Occurs in Dense Clusters Formed around Cohesin Anchor Sites.
Yan J*, Enge M*, Whitington T, Dave K, Liu J, Sur I, Schmierer B, Jolma A, Kivioja T, Taipale M,
Taipale J. *Equal contribution
Cell. 2013 Aug 15;154(4):801-13. doi: 10.1016/j.cell.2013.07.034.
10. DNA-Binding Specificities of Human Transcription Factors.
Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei
G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E,
Kivioja T, Taipale J.
Cell. 2013 Jan 17;152(1-2):327-39. doi: 10.1016/j.cell.2012.12.009.
11. MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and
growth arrest induced by pharmacologically activated p53.
Enge M, Bao W, Hedström E, Jackson SP, Moumen A, Selivanova G.
Cancer Cell. 2009 Mar 3;15(3):171-83.